Kevin Trudeau's book, 'The Weight Loss Cure,' made HCG a household name. HCG, a hormone extracted from the urine of pregnant women, is used to treat reproductive problems, but injections of the hormone are also thought to curb appetite. We suspect any weight loss might be the result of the 500-calorie-a-day diet you're supposed to follow on the plan, not necessarily the self- or doctor-adminstered shots. The FDA denies weight loss claims about HCG, but the hard-to-find shots are still widely sought after. Aside from the obvious ick factor, there are some intense side effects including water retention, mood alterations, headaches, and high blood pressure. Men who receive the injections may get positive results on pregnancy tests.